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"Kidney failure? How is it possible?" Uncle Li heard the doctor's words, so shocked that the whole person froze.
"A lot of patients who come here don't want to believe it, but your examination report is put here, creatinine is as high as 259, glomerular filtration index at 27.01ml/min, kidney damage is obvious, good thing it was found early, late it may develop into uremia." The doctor pointed to the checklist said.
It turns out that 68-year-old Uncle Li was found to have high blood pressure five years ago, and has been insisting on taking antihypertensive drugs. But recently, the number of times he urinated at night had increased significantly, his eyes and legs appeared puffy, and his whole body also felt weak, couldn't lift his spirits, and had a severe headache.
Doctors further inquired only to find that the original Uncle Li since the detection of high blood pressure five years ago, his habits have not changed much, still smoking and drinking, and often stay up late to eat late night snacks and so on.
While insisting on taking antihypertensive drugs, he has never measured his blood pressure. And he also took the liberty of changing his medication because he felt that the previous medication was too expensive, and his friend also said to him that "the effect of these antihypertensive drugs are the same, and long-term consumption of the same drug, not only hurt the kidneys, but also drug-resistant ......".
The doctor asked him about his previous medication and told him that "the previous medication, if taken normally, will not have an effect on kidney function". The doctor told him that if he took the medicine normally, it would not affect the kidney function.

One, long-term take a blood pressure medicine, will produce drug resistance?
High blood pressure patients need to take regular antihypertensive drugs to stabilize blood pressure, that long-term consumption of an antihypertensive drug, will produce drug resistance?
More than 90 percent of high blood pressure is primary, with no known cause, and cannot be cured for the time being. Taking antihypertensive drugs can only control blood pressure, but if you stop taking them, your blood pressure will still recur and you may have complications, so it is important for people with high blood pressure to take antihypertensive drugs regularly.
Resistance, which means that pathogenic microorganisms are resistant to the drugs, has led to a deterioration in the therapeutic effect of the previously effective drugs or failed.
The long-term use of antihypertensive drugs by hypertensive patients is mainly through the physiological mechanism to regulate the lowering of blood pressure levels, even if the duration of the medication is prolonged, this regulatory mechanism will not fail, so there is no need to worry about long-term use of antihypertensive drugs will produce drug resistance.
Even if you have been taking antihypertensive drugs for a long time and find that your blood pressure decreases, it's not because you're resistant to them. It could also be the result of aging, further aging of blood vessels, and the emergence of diseases such as hyperlipidemia and diabetes that affect overall blood pressure control.
Generally in the antihypertensive drugs to take a period of time after the blood pressure control is not ideal, or some adverse reactions to the need to change the drug, but even if the change in the drug needs to be under the guidance of the doctor, not at their own discretion change.

Second, taking antihypertensive drugs, will affect life expectancy?
Many patients are worried that long-term use of antihypertensive drugs will affect life expectancy, that taking antihypertensive drugs for a long time will not have a negative impact on the body?
Some patients worry that antihypertensive drugs hurt the liver and kidneys and then stop taking the drugs, but in fact, the doctor will consider the contraindications and indications when prescribing the drugs, and the general eating antihypertensive drugs will not appear to eat the kidneys bad situation.
And sartan or Prilosec antihypertensive drugs also have a renal protection effect, only standardized taking antihypertensive drugs to ensure that the blood pressure is up to standard, to reduce high blood pressure brought about by the kidney damage.
The real damage to the liver and kidneys is the uncontrollable blood pressure, the blood pressure is always high will lead to kidney blood vessel damage, and even trigger hypertensive nephropathy and renal failure.

There are also claims that long-term use of antihypertensive drugs will produce strong drug dependence, and the toxicity in the drug constantly destroys the brain, heart, kidneys and other organs, which may trigger some side effects such as nausea, asthma, dizziness and edema.
In fact, any drug may have side effects, and antihypertensive drugs are no exception. The side effects are relatively minor, and they are minimal compared to the harm caused by high blood pressure, so the benefits of taking antihypertensive drugs outweigh the disadvantages, and you can't avoid taking them.
In fact, antihypertensive drugs do not produce drug dependence, nor addiction, hypertensive patients can not leave the drug, because hypertension itself is a long-term, incurable chronic disease.
Once the medication is discontinued blood pressure may rebound and even jeopardize other organs, so antihypertensive drugs are taken to control blood pressure to protect the body's organs.

Three, keeping in mind the 3 principles, you can rest assured to eat antihypertensive drugs
For different groups of people, taking medication will inevitably lead to side effects, so what are the ways to reduce the impact of side effects brought about by antihypertensive drugs?
1, a small dose to start
The more the dose of side effects is also the greater, so taking antihypertensive drugs is best to start with a small dose, do not want to pursue want to increase the dose to improve the efficacy.
2, try to choose the long-acting drugs
Short-acting antihypertensive drugs have a relatively short duration of action, and the side effects are also larger, so it is best to choose the long-acting antihypertensive drugs.
3, joint use of drugs, if necessary, change the drug
One antihypertensive drug is not satisfactory, can be used in combination with two or three, it is recommended that small doses of joint use of drugs. For some antihypertensive drugs with obvious side effects, the drug can be discontinued under the guidance of a doctor and replaced in a timely manner.

While drugs have some side effects, the side effects of taking antihypertensive drugs in general are far less harmful than those of high blood pressure, so patients with high blood pressure should regularly follow the doctor's instructions for medication.
- Author:Duly-health
- URL:https://www.dulyhealth.site/article/f27e56ce-ae97-4813-a3c0-ecbb6455b2d3
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